- Active Substance: Tirzepatide
- Concentration: 10 mg
- Pack Size: pen
- Manufacturer: Ultima Pharmaceuticals
- Brand Name: Tirzepatide
SKU: P4131
Achieve Significant Weight Management and Improved Blood Sugar Control with Ultima-Ultrajaro 10mg Pen
You're looking at Ultima-Ultrajaro (Tirzepatide), a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. This medication is primarily indicated for the management of type 2 diabetes and has also demonstrated significant effectiveness in weight loss. Ultima-Ultrajaro leverages the power of dual incretin receptor agonism to help regulate blood sugar and promote substantial weight reduction.
Key Features:
- Dual GIP and GLP-1 Receptor Agonist: Activates both GIP and GLP-1 receptors, leading to enhanced metabolic effects.
- Significant Weight Loss: Clinical trials have shown substantial weight reduction in individuals using Tirzepatide.
- Improved Blood Sugar Control: Effectively lowers HbA1c levels and improves glycemic control in type 2 diabetes.
- Appetite Regulation: Helps reduce appetite and increase feelings of fullness.
- Single-Use Pen: Convenient and easy-to-use injectable format.
- 10 mg Concentration: A specific dosage available in the Ultima-Ultrajaro pen. Dosage titration is typically required under medical supervision.
- Ultima Pharmaceuticals: A manufacturer of pharmaceutical-grade products.
Mechanism of Action:
Ultima-Ultrajaro contains Tirzepatide, a synthetic peptide that mimics the actions of both GIP and GLP-1, which are incretin hormones. These hormones are released from the gut in response to food intake and play crucial roles in glucose homeostasis and appetite regulation:
- GLP-1 Receptor Agonism: Stimulates insulin secretion in a glucose-dependent manner, inhibits glucagon secretion, slows gastric emptying, and promotes satiety in the brain.
- GIP Receptor Agonism: Also stimulates insulin secretion (though its effect is diminished in type 2 diabetes), may improve insulin sensitivity, and has effects on fat metabolism and adipose tissue.
By activating both receptors, Tirzepatide can have more pronounced effects on blood glucose control and weight loss compared to GLP-1 receptor agonists alone.
Benefits:
- Significant Weight Reduction: Often greater weight loss compared to GLP-1 receptor agonists.
- Improved Glycemic Control: Lowers HbA1c and fasting blood glucose levels.
- Reduced Appetite and Food Intake.
- Potential Cardiovascular Benefits: Studies have suggested potential positive effects on cardiovascular outcomes in individuals with type 2 diabetes.
- Convenient Once-Weekly Injection.
Use in Combination:
Ultima-Ultrajaro is primarily used in the management of type 2 diabetes and weight loss. Its use in combination with other medications should be under the guidance of a healthcare professional:
- Diabetes Medications: May be used in conjunction with other oral antidiabetic drugs (OADs) like metformin or SGLT-2 inhibitors, under careful medical supervision to avoid hypoglycemia.
- Insulin: Can be used with insulin in some cases, with close monitoring of blood glucose levels.
- Weight Loss Medications: Combining with other weight loss drugs is generally not recommended unless specifically advised by a healthcare provider.
Possible Applications:
- Management of Type 2 Diabetes Mellitus in Adults.
- Weight Management in Adults with Obesity or Overweight with at Least One Weight-Related Comorbidity.
Usage Guidelines:
Ultima-Ultrajaro is administered via subcutaneous injection using the provided pen. Dosage and titration schedule should be strictly followed as prescribed by a healthcare professional:
- Administration: Subcutaneous injection, typically in the thigh, abdomen, or upper arm. Follow the instructions provided with the pen.
- Dosage: The starting dose is typically lower (e.g., 2.5 mg once weekly) and gradually increased over several weeks to the target maintenance dose (e.g., 5 mg, 10 mg, or 15 mg once weekly) based on individual response and tolerability. The 10 mg pen represents one of the possible maintenance dosages.
- Frequency: Once weekly injection. It's recommended to administer the injection on the same day each week.
- Storage: Store the pen in the refrigerator as indicated in the product instructions.
Potential Side Effects:
Common side effects associated with Tirzepatide are primarily gastrointestinal and usually mild to moderate in severity:
- Nausea.
- Vomiting.
- Diarrhea.
- Constipation.
- Abdominal Pain.
- Decreased Appetite.
- Hypoglycemia (low blood sugar), especially when used with other diabetes medications like insulin or sulfonylureas.
Rare but serious side effects can occur. It's crucial to discuss the potential risks and benefits with a healthcare provider.
Important Considerations:
- Prescription Medication: Tirzepatide is a prescription medication and should only be used under the guidance of a qualified healthcare professional.
- Not for Type 1 Diabetes: It is not indicated for use in individuals with type 1 diabetes.
- Thyroid C-cell Tumors: In animal studies, Tirzepatide caused thyroid C-cell tumors. It is unknown whether this occurs in humans. Individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not use Tirzepatide.
- Pancreatitis: Pancreatitis has been reported in clinical trials. Monitor for signs and symptoms.
What is Ultima-Ultrajaro (Tirzepatide)?
Ultima-Ultrajaro contains Tirzepatide, a dual GIP and GLP-1 receptor agonist used for the management of type 2 diabetes and weight loss.
What are the main benefits of Tirzepatide?
The main benefits include significant weight loss and improved blood sugar control.
How is Ultima-Ultrajaro administered?
It is administered via subcutaneous injection once weekly using a single-use pen.
What are the potential side effects?
Common side effects are primarily gastrointestinal, such as nausea, vomiting, and diarrhea. More serious side effects are possible, and it's important to consult with a healthcare provider.